BGI STOmics® Grant
Expressions of Interest Now Open!
BGI Australia is offering an exclusive grant for Oz Single Cell 2021 attendees to award early access to BGI latest spatial omics innovation STOmics®. The grant will award the Winner a $50,000-worth BGI STOmics® kit, including STOmics® Fluorescent Set and STOmics® Gene Expression Set, suitable for processing up to a total of 4 samples. We are now accepting Expressions of Interest(EOI)*!
Conditions:
- Human samples are not applicable.
- The sequencing will be performed by BGI Research, China.
- The project will be initiated no later than March 2022.
How to apply:
Please email your EOI to BGI-Australia@genomics.cn including your name, department/institute, contact information, and details about your project, sample/s, proposed experiment, and any reference information. Please include BGI STOmics® Grant in your subject line in your EOI. If you have any questions regarding the grant you may contact BGI Australia Marketing or Decode Science. The EOIs will be reviewed within 2 weeks upon submission.
*This grant is an exclusive offer for Oz Single Cell 2021 attendees. Applications will close on 26th November.
Method of the Year: spatially resolved transcriptomics, Nature Methods
"....Xun Xu, CEO of BGI Group, who directs BGI Research. He watches other company activities in this area and believes the BGI approach will have the highest resolution. The approach captures a few hundred data points per cell, says Xu." Nature Methods spotted great potential in BGI spatial omics innovation is featured in January 2021.
How it Works
BGI STOmics® and Stereo-Seq™
BGI STOmics® is a pioneer in advancing spatially-resolved transcriptomic analysis through its proprietary Stereo-Seq™ (SpaTial Enhanced REsolution Omics-Sequencing) technology. Built on DNA Nanoball (DNB) technology, Stereo-Seq™ offers researchers a novel tool to explore spatial biology with unprecedented field-of-view and resolution.
Stereo-Seq™ is performed in square-centimeter units, with the standard 1x1 cm RNA capture unit employing the STOmics-GeneExpression-S1 Chip. STOmics-GeneExpression-S1 combines centimeter-field-of-view in situ capture of whole transcriptome information with nanoscale resolution, powering the unrivaled quality of Stereo-Seq. STOmics-GeneExpression-S1 enables researchers to perform spatial transcriptomic analysis at the tissue, cellular, subcellular, and molecular levels within one tissue sample.
Application Example: Visualizing Whole Mouse Embryos and Adult Mouse Brains Through Stereo-Seq
STOmics-GeneExpression-S1 Chips are patterned grids of probes containing spatial coordinates. Upon interaction with a tissue section, cDNA is synthesized in situ from mRNA captured by the chip probes. Sequencing the cDNA with their spatial coordinates allows in silico reconstitution of the spatial transcriptomic profile of the tissue section, allowing easy visualization and analysis.
STOmics-GeneExpression-S1 resolves the developmental structure-specific gene expression patterns in mouse embryos at centimeter-scale fields of view. A. Hematoxylin and eosin staining of an E16.5 embryo section. B. Unsupervised clustering analysis identifies different anatomical structures in the E16.5 embryo. C. Spatial expression heatmap of the indicated genes representing different developing structures in an E16.5 embryo section.